Health Technology Assessment

Australian Industry Strikes Deal On Deferred PBS Submissions, Challenges Govt's Capacity Claim

Australian Industry Strikes Deal On Deferred PBS Submissions, Challenges Govt's Capacity Claim

 

Medicines Australia has expressed skepticism over the Pharmaceutical Benefits Advisory Committee’s claim that in March 2025 it will only be able to assess 32 submissions from companies that want to get their drugs subsidized under the Pharmaceutical Benefits Scheme.

EU HTA Reg: CoI Rules Limit Participation Of Experts In Joint Clinical Assessments

EU HTA Reg: CoI Rules Limit Participation Of Experts In Joint Clinical Assessments

 

The European Commission has now adopted the third implementing act for the Health Technology Assessment Regulation. This sets out rules for managing conflicts of interest of anyone involved in joint clinical assessments or joint scientific consultations under the regulation.

EU HTA Regulation: Assessors Risk Exclusion for Secrecy Breaches

EU HTA Regulation: Assessors Risk Exclusion for Secrecy Breaches

 

The second of six implementing acts for the Health Technology Assessment Regulation has now been adopted. It deals with how the European Medicines Agency is to cooperate with the European Commission and HTA experts in Europe.

Déjà Vu In England: Lilly’s Alzheimer’s Drug Kisunla Gets MHRA Yes, But NICE Says No

Déjà Vu In England: Lilly’s Alzheimer’s Drug Kisunla Gets MHRA Yes, But NICE Says No

 

The UK’s drug regulator has approved Eli Lilly’s early Alzheimer’s drug Kisunla, but England’s health technology assessment agency NICE said that the product “does not currently demonstrate value” for the National Health Service.


Nordic HTA Collaboration: Feel The Fear And Do It Anyway

Nordic HTA Collaboration: Feel The Fear And Do It Anyway

 

It is time for companies to take part in cross-country health technology assessments and stop asking “what’s in it for me?”

Has Competition Reassurance Helped Counter Combination Woes In The UK?

Has Competition Reassurance Helped Counter Combination Woes In The UK?

 
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The rate of non-submissions for combination therapies in England has been on a downward trend in the last two years.

EU HTA Regulation: ‘We Don’t Want An Empty Dossier,’ Warns Coordination Group

EU HTA Regulation: ‘We Don’t Want An Empty Dossier,’ Warns Coordination Group

 

Manufacturers that do not answer all questions they are asked during joint clinical assessments under the upcoming EU HTA Regulation could have their applications deemed incomplete, says a co-chair of the JCA subgroup.

EU HTA Regulation: Views Wanted On Draft Rules On Joint Scientific Consultations

EU HTA Regulation: Views Wanted On Draft Rules On Joint Scientific Consultations

 

A newly published draft implementing act sets out the procedural rules for the joint scientific consultations that are foreseen by the EU’s Health Technology Assessment Regulation.


England’s NICE Says Severity Modifier Working, But Industry Wants Cost Restrictions Lifted

England’s NICE Says Severity Modifier Working, But Industry Wants Cost Restrictions Lifted

 

The UK government should remove a cost-neutrality restriction on England’s health technology assessment institute, NICE, that limits the value it places on medicines for severe conditions, says industry body the ABPI.

EUCOPE: EU Pharma Reform Positive, But Industry Needs Clearer Definitions

EUCOPE: EU Pharma Reform Positive, But Industry Needs Clearer Definitions

 

High unmet needs is among the terms and definitions in the EU’s regulatory reform package that are “very subjective” and require more clarity to improve predictability for the pharmaceutical industry, EUCOPE’s secretary general, Alexander Natz, tells the Pink Sheet.

New EU HTA Guidance OKs Single-Arm Studies, But More Work Needed On Evidence Gaps

New EU HTA Guidance OKs Single-Arm Studies, But More Work Needed On Evidence Gaps

 

New guidance from the European Commission on clinical trial validity for forthcoming joint clinical assessments has eased some concerns about the generation of evidence for rare disease treatments and advanced therapies.

HTA Regulation: EU Publishes Guidance On Validity Of  Clinical Studies For Joint Clinical Assessments

HTA Regulation: EU Publishes Guidance On Validity Of Clinical Studies For Joint Clinical Assessments

 

Joint clinical assessment reports must be descriptive rather than reach definitive conclusions, and must not interfere with national decision making processes, according to new EU guidance.


EU HTA Regulation: Some Member States Could Be ‘Deselected’ From Joint Assessments

EU HTA Regulation: Some Member States Could Be ‘Deselected’ From Joint Assessments

 

The EU HTA Regulation will see clinical comparisons of medical products conducted at an EU level. However, the needs of some smaller nations may not be represented, experts from Cencora explain in this second of two articles on the new EU joint clinical assessments.

EU HTA Regulation: Expect The Unexpected When It Comes To PICOs

EU HTA Regulation: Expect The Unexpected When It Comes To PICOs

 

Manufacturers should undertake scenario planning exercises and simulations to prepare for questions that will be asked under the upcoming EU HTA Regulation, but unpredictable questions are likely to arise, experts from Cencora caution in this first of two articles on the new EU joint clinical assessments.

Ipsen On Working With The UK’s Health Authorities To Make Industry’s Voice Heard

Ipsen On Working With The UK’s Health Authorities To Make Industry’s Voice Heard

 

Improvements in the UK’s manufacturing and clinical trial ecosystems are on the “Christmas list” of Ioana Parsons, Ipsen’s general manager for the UK & Ireland.

Saudi Arabia To Mandate Economic Evaluation Studies For New Drugs From July 2025

Saudi Arabia To Mandate Economic Evaluation Studies For New Drugs From July 2025

 
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Companies marketing pharmaceutical products in Saudi Arabia are being urged to prepare for upcoming mandatory pharmacoeconomic assessments to demonstrate the added value of their drugs over existing treatments.


No UK Approval Filing For Biogen's Tofersen Because Of NICE HTA Decision

No UK Approval Filing For Biogen's Tofersen Because Of NICE HTA Decision

 
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England’s health technology assessment body, NICE, says it has suspended the appraisal process for the motor neurone disease treatment while it considers the next steps. No HTA submission for tofersen has been made in Scotland.

Australia Considers New 'Bridging Fund' Among 50 Recommendations For HTA Reform

Australia Considers New 'Bridging Fund' Among 50 Recommendations For HTA Reform

 

Industry says it is ready to work with the government on the recommendations from a major review of Australia’s health technology assessment system that covers areas such as discount rate reductions and setting up a separate budgetary allocation to temporarily subsidize access to certain drugs.

Would National US HTA/Price Negotiation Process Slow Drug Access? Maybe Not

Would National US HTA/Price Negotiation Process Slow Drug Access? Maybe Not

 
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Research published in the Annals of Internal Medicine finds the US time from a drug’s approval to reimbursement is not the swiftest, compared to countries in Europe.

Spain Consults On Plans To Regulate HTAs

Spain Consults On Plans To Regulate HTAs

 

New rules on health technology assessments in Spain make room for real-world evidence and early dialogue.