Drug Pricing

PBMs, FTC and IRA: Experts Tackle Pharma’s Tough Acronyms At BioFuture

PBMs, FTC and IRA: Experts Tackle Pharma’s Tough Acronyms At BioFuture

 

Some of the industry’s biggest challenges – and potential solutions to those problems – were hot topics at the BioFuture conference in New York.

India Rare Diseases: Court Shows Path For Policy Action, Funding, Price Issues

India Rare Diseases: Court Shows Path For Policy Action, Funding, Price Issues

 

A court order encompassing funding, drug pricing, clinical trials and overall policy implementation aspects is expected to bring about a paradigm shift in the treatment of rare diseases in India. Sarepta, Roche and Sanofi are among the key players that have been part of pricing discussions.

Manufacturers Eye Challenges Of Broadening Cell And Gene Therapy Access

Manufacturers Eye Challenges Of Broadening Cell And Gene Therapy Access

 
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With more advanced therapies gaining approval, companies at ARM’s Cell and Gene Meeting on the Mesa considered hurdles to making their products more broadly available and developing them for larger indications.

GSK’s Arexvy Reinforces Its Lead In A Stalling RSV Vaccine Market

GSK’s Arexvy Reinforces Its Lead In A Stalling RSV Vaccine Market

 

Arexvy has become the first RSV vaccine to show it can provide protection over three years – but that might mean lower market uptake than originally expected.


Gilead Seals VLs For Lenacapavir Amid Concerns Around Price, API Supplies

Gilead Seals VLs For Lenacapavir Amid Concerns Around Price, API Supplies

 

Gilead strikes voluntary licensing agreements with six generic manufacturers for lenacapavir but health groups seek clarity on pricing and seeming API supply restrictions. All eyes are also on the patent opposition case in India.

GLP-1s For Obesity: Maximalists, Skeptics And ‘No Sales Targets’

GLP-1s For Obesity: Maximalists, Skeptics And ‘No Sales Targets’

 

A high-profile panel that included a senior executive from F-Prime Capital, Novo Nordisk's India chief and a leading endocrinologist discussed, at a recent event, some of the big opportunities, challenges and transformational trends underway as obesity drugs take the world by storm.

Zevra’s Miplyffa Wins First-Ever US Approval, But In Combination With Off-Label Miglustat

Zevra’s Miplyffa Wins First-Ever US Approval, But In Combination With Off-Label Miglustat

 
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Miplyffa (arimoclomol) was approved for Niemann-Pick disease type C when administered with another high-priced drug used off label as standard of care for about 80% of NPC patients. 

Gilead Hits Mark With Second Long-Acting HIV PrEP Trial

Gilead Hits Mark With Second Long-Acting HIV PrEP Trial

 

The company stands a strong chance of winning approval for lenacapavir as a twice-yearly injectable drug for preventing HIV infection, though market challenges remain.


Travere Set For Big Expansion As Filspari Wins Full Approval In IgAN

Travere Set For Big Expansion As Filspari Wins Full Approval In IgAN

 

The drug maker could end up doubling the addressable patient population for Filspari thanks to the new label removing the proteinuria threshold, plus a draft treatment guideline from a kidney disease group.

Vaxcyte Confident Of Pneumococcal Vaccine Dominance After Phase I/II Results

Vaxcyte Confident Of Pneumococcal Vaccine Dominance After Phase I/II Results

 
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The company’s VAX-31 against 31 pneumococcal serotypes outperformed Pfizer’s market-leading Prevnar 20 and could provide the broadest coverage of any vaccine in its class.

Lilly To Offer Zepbound Single-Dose Vials To Self-Pay Consumers

Lilly To Offer Zepbound Single-Dose Vials To Self-Pay Consumers

 

The company is offering Zepbound in single-dose 2.5mg and 5mg vials, both to expand supply and access, especially for patients without coverage for the obesity drug. 

Merck’s Winrevair Approved For PAH In Europe As Initial US Launch Progresses

Merck’s Winrevair Approved For PAH In Europe As Initial US Launch Progresses

 
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Merck & Co. won European Commission approval for Winrevair on top of other medicines for pulmonary arterial hypertension and expects an initial EU launch in Germany.


Quick Listen: Scrip's Five Must-Know Things

Quick Listen: Scrip's Five Must-Know Things

 
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In this week's podcast edition of Five Must-Know Things: CMS’s price reveal better than expected?; new diabetes risk data for Zepbound; can J&J’s lung cancer combo stand up to Tagrisso?; new recruits for BioMarin leadership; and Glenmark’s shifting revenues.

England’s Cost Effectiveness Rejection Is Another Setback For Eisai And Biogen’s Leqembi

England’s Cost Effectiveness Rejection Is Another Setback For Eisai And Biogen’s Leqembi

 

Cost watchdog NICE has blocked Leqembi’s use, but a pricing deal could unlock access to the beta-amyloid targeting drug

CMS’s Big Drug Price Reveal Turns Out Better For Pharma Than Feared

CMS’s Big Drug Price Reveal Turns Out Better For Pharma Than Feared

 

The first round of US government drug price negotiations resulted in prices for 10 drugs that will lower aggregate net spending by 22%

Lupin: Glad To Have Dodged Humira Bullet, Lucentis Biosimilar Closer As Phase III Trials Succeed

Lupin: Glad To Have Dodged Humira Bullet, Lucentis Biosimilar Closer As Phase III Trials Succeed

 
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Lupin’s CEO highlights market access strategy as a key tool to ensure biosimilars success in the US while being relieved the company didn’t launch a Humira biosimilar. She also mentions Amazon and Mark Cuban have not upset market dynamics for generics in the US and a Lucentis biosimilar is closer to a global launch post Phase III trial success


AstraZeneca’s Enhertu Expansion Blocked By NICE Over Price

AstraZeneca’s Enhertu Expansion Blocked By NICE Over Price

 

The cost effectiveness watchdog claims AstraZeneca and Daiichi-Sankyo have not offered a fair price for use in the larger HER2-low setting.

BMS ‘Increasingly Confident’ It Can Handle The Impact Of Medicare Pricing For Eliquis

BMS ‘Increasingly Confident’ It Can Handle The Impact Of Medicare Pricing For Eliquis

 
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Bristol’s CEO offered assurances about Medicare negotiations under the IRA as the company delivered better-than-expected second quarter results across new and legacy products.

RemeGen Rises, Falls Along With Chinese Antibody Ambitions

RemeGen Rises, Falls Along With Chinese Antibody Ambitions

 
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Everything seemed to be aligned for success, but shares in leading Chinese antibody developer RemeGen recently dropped by nearly 40%, reflecting a range of internal and external likely factors.

Farxiga Flying Off The Shelf At AstraZeneca

Farxiga Flying Off The Shelf At AstraZeneca

 
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The UK major has raised its full-year sales and earnings forecast on strong demand in the second quarter for its cancer, rare disease and cardiovascular medicines.